Mansell Research Group at Iowa State University

Publications

2019

  1. Enam F, Kramer E, Ryerson L, Robinson F, Mansell TJ. Rapid paper-based sensing of fucosylated biological compounds. (in preparation)
  2. Rothstein SM, Enam F, Sun W, Chávez-Santoscoy M, Jarboe LR, Shao Z, Mansell TJ. Engineered probiotics and synbiotics: designing bacteria for human health (in revision)
  3. Bai Y, Saldanha J, Powell-Coffman JA, Mansell TJ. Production and sensing of butyrate in a probiotic strain of Escherichia coli. (in revision)
  4. Sun L, Rollins D, Mansell TJ, Fredericks J, Jergens A, Phillips GJ, Wannemuehler MJ, Wang Q. Studies of Miniguts Isolated from Mice with Both Defined and Conventional Microbiota (in revision)
  5. Sen S, Mansell TJ. Yeast as probiotics: mechanisms, outcomes, and future potential (submitted)
  6. Enam F, Mansell TJ. Prebiotics: Tools to manipulate the gut microbiome and metabolome J. Ind. Microbiol. Biotechnol. (in press) 2019
  7. Zainuddin H, Bai Y, Mansell TJ. CRISPR-based curing and analysis of metabolic burden of cryptic plasmids in Escherichia coli Nissle 1917  Eng. Life Sci. 19: 478– 485 2019
  8. Enam F, Mansell TJ. Analysis of Fucosylated Human Milk Trisaccharides in Biotechnological Context Using Genetically Encoded Biosensors. J. Vis. Exp. (146), e59253 2019.

2018

  1. Dopp JL, Rothstein SM, Mansell TJ, Reuel NF. Rapid Prototyping of Proteins: Mail Order Gene Fragments to Assayable Proteins Within 24 Hours Biotechnology and Bioengineering 1 2018
  2. Enam F, Mansell TJ. Linkage-specific detection and metabolism of human milk oligosaccharides in Escherichia coli Cell Chemical Biology 25 (10), 1292-1303. e4 1 2018
  3. Chen Y, Reinhardt M, Neris N, Kerns L, Mansell TJ, Jarboe LR. Lessons in membrane engineering for octanoic acid production from environmental Escherichia coli isolates
    Appl. Environ. Microbiol. 84 (19), e01285-18 2018

2017

  1. Wayman JA, Glasscock C, Mansell TJ, DeLisa MP, Varner J. Improving Designer Glycan Production in Escherichia coli through Model-Guided Metabolic Engineering  bioRxiv, 160853 (in revision)

2016

  1. Weiss SJ*, Mansell TJ*, Mortazavi P, Knight R, Gill RT. Parallel Mapping of Antibiotic Resistance Alleles in Escherichia coli. PLoS One. 2016;11(1):e0146916. doi: 10.1371/journal.pone.0146916.

2015

  1. Robinson MP, Ke N, Lobstein J, Peterson C, Szkodny A, Mansell TJ, Tuckey C, Riggs PD, Colussi PA, Noren CJ, Taron CH, DeLisa MP, Berkmen M. Efficient expression of full-length antibodies in the cytoplasm of engineered bacteria. Nat Commun. 2015 Aug 27;6:8072. doi: 10.1038/ncomms9072
  2. Zeitoun RI, Garst AD, Degen GD, Pines G, Mansell TJ, Glebes TY, Boyle NR, Gill RT. Multiplexed tracking of combinatorial genomic mutations in engineered cell populations. Nat Biotechnol. 2015 Jun;33(6):631-7. doi: 10.1038/nbt.3177.

2013

  1. Mansell TJ, Guarino C, DeLisa MP. Engineered genetic selection links in vivo protein folding and stability with asparagine-linked glycosylation. Biotechnol J. 2013 Dec;8(12):1445-51. doi: 10.1002/biot.201300026.
  2. Mansell TJ, Warner JR, Gill RT. Trackable multiplex recombineering for gene-trait mapping in E. coli. Methods Mol Biol. 2013;985:223-46. doi:10.1007/978-1-62703-299-5_12.

pre-2013

  1. Celik E, Fisher AC, Guarino C, Mansell TJ, DeLisa MP. A filamentous phage display system for N-linked glycoproteins. Protein Sci. 2010 Oct;19(10):2006-13. doi:10.1002/pro.472.
  2. Mansell TJ, Linderman SW, Fisher AC, DeLisa MP. A rapid protein folding assay for the bacterial periplasm. Protein Sci. 2010 May;19(5):1079-90. doi:10.1002/pro.388.
  3. Lim HK, Mansell TJ, Linderman SW, Fisher AC, Dyson MR, DeLisa MP. Mining mammalian genomes for folding competent proteins using Tat-dependent genetic selection in Escherichia coli. Protein Sci. 2009 Dec;18(12):2537-49. doi:10.1002/pro.262.
  4. Conrado RJ, Mansell TJ, DeLisa MP “Engineering multifunctional enzyme systems for optimized metabolite transfer between sequential conversion steps” in The Metabolic Pathway Engineering Handbook. 2009 Edited by CD Smolke: CRC Press doi: 10.1201/9781420077667.ch11
  5. Mansell TJ, Fisher AC, DeLisa MP. Engineering the protein folding landscape in gram-negative bacteria. Curr Protein Pept Sci. 2008 Apr;9(2):138-49. doi: 10.2174/138920308783955243
  6. Fisher AC, Mansell TJ, DeLisa MP. “Protein Folding and Solubility: Pathways and High-Throughput Assays” in Protein Engineering Handbook. 2008 Edited by S Lutz and UT Bornscheuer: Wiley-VCH doi: 10.1002/9783527634026.ch5
  7. 1-s2.0-S1096717607X00387-cov150hConrado RJ, Mansell TJ, Varner JD, DeLisa MP. Stochastic reaction-diffusion simulation of enzyme compartmentalization reveals improved catalytic efficiency for a synthetic metabolic pathway. Metab Eng. 2007 Jul;9(4):355-63. doi:10.1016/j.ymben.2007.05.002
  8. Liang J, Kim JR, Boock JT, Mansell TJ, Ostermeier M. Ligand binding and allostery can emerge simultaneously. Protein Sci. 2007 May;16(5):929-37. doi: 10.1110/ps.062706007
  9. Guntas G, Mansell TJ, Kim JR, Ostermeier M. Directed evolution of protein switches and their application to the creation of ligand-binding proteins. Proc Natl Acad Sci U S A. 2005 Aug 9;102(32):11224-9. doi: 10.1073/pnas.0502673102